Dr Amirmalek graduated with a Doctor of Medicine degree from Tehran Medical School of Azad University, Iran, in 2002. He obtained registration with the General Medical Council of the United Kingdom in 2006 and received his Australian Medical Council certificate in 2013. In 2020, he was awarded Fellowship of the Royal Australian College of Physicians.

He completed a fellowship in lung cancer and interventional pulmonology at Sir Charles Gairdner and Fiona Stanley hospitals. Dr Amirmalek specialises in pleural diseases, lung nodules, thoracic malignancies, and is an expert in medical pleuroscopy. His clinical interests also include sleep-disordered breathing, asthma, COPD, interstitial lung diseases, and pulmonary vascular diseases.

Currently, he serves as a Respiratory Physician and Staff Specialist on the Central Coast, Director of Training at Bankstown Hospital, and a Respiratory Visiting Medical Officer at Bankstown Hospital.

Dr Amirmalek is a member of the Thoracic Society of Australia and New Zealand, European Respiratory Society, Asian Pacific Society of Respirology, World Association for Bronchology and Interventional Pulmonology, and Lung Foundation Australia.